DBCO acid 4
CAS No. 1618102-42-3
DBCO acid 4( —— )
Catalog No. M12370 CAS No. 1618102-42-3
DBCO acid 4 is a Click Chemistry intermidate used for antibody-drug conjugates.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameDBCO acid 4
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NoteResearch use only, not for human use.
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Brief DescriptionDBCO acid 4 is a Click Chemistry intermidate used for antibody-drug conjugates.
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DescriptionDBCO acid 4 is a Click Chemistry intermidate used for antibody-drug conjugates.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayAntibody Drug Conjugates (ADC)
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TargetADCs Linker/Click Chemistry
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RecptorADCs Linker/Click Chemistry
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Research Area——
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Indication——
Chemical Information
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CAS Number1618102-42-3
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Formula Weight376.412
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Molecular FormulaC22H20N2O4
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical Name4-[[3-(11,12-Didehydrodibenz[b,f]azocin-5(6H)-yl)-3-oxopropyl]amino]-4-oxobutanoic acid
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Kheirabadi M, et al. J Org Chem. 2018 Apr 20;83(8):4323-4335.
2. Alam S, et al. Bioconjug Chem. 2015 Jun 17;26(6):1021-31.
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DSS Crosslinker
DSS Crosslinker is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).It is a homobifunctional crosslinker that is cell membrane permeable. DSS crosslinker has amine-reactive NHS esters at both ends of an 8-atom (11.4 angstrom) spacer arm that are used to conjugate proteins.
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